Both men and women produce varying degrees of estrogen and testosterone. There's some evidence that men who are low in estrogen or related hormones may have an increased risk of osteoporosis and cardiovascular disease. Elevated estrogen may increase the risk of benign prostatic hyperplasia (prostate gland enlargement) as well as prostate cancer.

Important: Men who are at high risk for prostate disease-due to an elevated prostate-specific antigen (PSA) test or an abnormally sized or shaped prostate-or those experiencing low energy, a decrease in libido or other symptoms associated with a hormonal imbalance, should ask their doctors to include estrogen as part of a wide-spectrum hormonal screening test.

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